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Peter B Barker Selected Research

Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)

12/2012Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.

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Peter B Barker Research Topics

Disease

17Neoplasms (Cancer)
08/2023 - 12/2004
9Schizophrenia (Dementia Praecox)
01/2022 - 03/2011
7Cognitive Dysfunction
11/2021 - 04/2005
5Brain Neoplasms (Brain Tumor)
03/2024 - 02/2006
5Glioblastoma (Glioblastoma Multiforme)
08/2023 - 01/2022
5HIV Infections (HIV Infection)
01/2020 - 02/2010
4Glioma (Gliomas)
01/2021 - 11/2013
3Psychotic Disorders (Schizoaffective Disorder)
03/2024 - 01/2019
3Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
04/2023 - 10/2002
3Restless Legs Syndrome (Restless Legs)
01/2016 - 02/2009
2Mitochondrial Diseases (Mitochondrial Disease)
01/2023 - 01/2003
2Central Nervous System Diseases (CNS Diseases)
01/2023 - 03/2014
2Astrocytoma (Pilocytic Astrocytoma)
01/2021 - 05/2005
2Brain Diseases (Brain Disorder)
01/2019 - 05/2018
2Dementia (Dementias)
01/2018 - 02/2010
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
02/2014 - 08/2013
2Multiple Sclerosis
12/2012 - 05/2012
2Atrophy
02/2012 - 06/2011
2Breast Neoplasms (Breast Cancer)
12/2010 - 01/2004
2Infections
10/2010 - 02/2010
2Sarcoma (Soft Tissue Sarcoma)
07/2010 - 06/2007
2Bone Cysts (Bone Cyst)
07/2010 - 06/2007
2Neurofibroma
07/2010 - 06/2007
2Lipoma (Lipomata)
07/2010 - 06/2007
2Hematoma
07/2010 - 01/2005
2Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome)
08/2006 - 10/2003
1Demyelinating Diseases (Demyelinating Disease)
04/2023
1Ataxia (Dyssynergia)
12/2022
1Substance-Related Disorders (Drug Abuse)
01/2022
1Mental Disorders (Mental Disorder)
01/2022
1Nocturnal Enuresis (Bedwetting)
12/2021
1Mood Disorders (Mood Disorder)
11/2021
1Major Depressive Disorder (Major Depressive Disorders)
11/2021
1Ketosis
01/2021
1Encephalitis (Encephalitis, Rasmussen)
01/2018
1Facioscapulohumeral Muscular Dystrophy
01/2018
1succinic semialdehyde dehydrogenase deficiency
07/2016
1Iron Deficiencies
01/2016
1Alzheimer Disease (Alzheimer's Disease)
05/2015
1Intracranial Hemorrhages (Intracranial Hemorrhage)
07/2014
1Ischemic Stroke
07/2014
1Myositis (Idiopathic Inflammatory Myopathies)
07/2013
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2012
1Disease Progression
01/2012
1Pathologic Complete Response
12/2010
1Virus Diseases (Viral Diseases)
10/2010
1Giant Cell Tumors (Giant Cell Tumor)
07/2010

Drug/Important Bio-Agent (IBA)

32Protons (Proton)IBA
03/2024 - 05/2002
9Choline (Choline Chloride)IBA
07/2023 - 01/2006
8N-acetylaspartate (N-acetyl aspartate)IBA
03/2024 - 01/2005
7Glutamic Acid (Glutamate)FDA Link
01/2021 - 01/2009
6Biomarkers (Surrogate Marker)IBA
07/2023 - 01/2012
5gamma-Aminobutyric Acid (GABA)IBA
12/2021 - 01/2013
4AmidesIBA
08/2023 - 11/2013
4Lactic Acid (Lactate)FDA LinkGeneric
01/2023 - 01/2003
4Glutamine (L-Glutamine)FDA Link
04/2016 - 01/2009
3Glutathione (Reduced Glutathione)IBA
05/2023 - 05/2018
3Indicators and Reagents (Reagents)IBA
01/2021 - 11/2010
2N-(gamma-aminobutyryl)glutamic acidIBA
01/2021 - 09/2013
2Aminobutyrates (Aminobutyric Acid)IBA
07/2016 - 05/2015
2GadoliniumIBA
11/2013 - 09/2007
2Neurotransmitter Agents (Neurotransmitter)IBA
09/2013 - 08/2013
2SodiumIBA
12/2010 - 12/2004
125-hydroxyvitamin DIBA
04/2023
1Cholecalciferol (Vitamin D3)FDA Link
04/2023
1Vitamin DFDA LinkGeneric
04/2023
1Temozolomide (Temodar)FDA LinkGeneric
01/2022
1belinostatIBA
01/2022
1Psilocybin (Psilocibin)IBA
11/2021
1KetonesIBA
01/2021
1Antipsychotic Agents (Antipsychotics)IBA
01/2021
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021
1Messenger RNA (mRNA)IBA
12/2020
1metabotropic glutamate receptor 3 (mGluR3)IBA
12/2020
1Polytetrafluoroethylene (Teflon)FDA Link
01/2019
1AntioxidantsIBA
05/2018
1Succinate-Semialdehyde Dehydrogenase (Succinic Semialdehyde Dehydrogenase)IBA
07/2016
1AcidsIBA
07/2016
1IronIBA
01/2016
1Tissue Plasminogen Activator (Alteplase)FDA Link
07/2014
1APTIBA
11/2013
1isospaglumic acid (NAAGA)IBA
09/2013
1NeuropeptidesIBA
09/2013
1Butyric Acid (Butanoic Acid)IBA
01/2013
1Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA
12/2012
1Glutamate Receptors (Glutamate Receptor)IBA
03/2011
1N-Methylaspartate (NMDA)IBA
03/2011
1Estrogen ReceptorsIBA
12/2010
1Immunologic Factors (Immunomodulators)IBA
10/2010
1Macrophage Colony-Stimulating FactorIBA
10/2010

Therapy/Procedure

11Therapeutics
04/2023 - 01/2005
3Highly Active Antiretroviral Therapy (HAART)
01/2018 - 06/2011
2Radiotherapy
01/2023 - 01/2022
2Aftercare (After-Treatment)
01/2019 - 07/2014
1Activities of Daily Living (ADL)
12/2022
1Transcranial Magnetic Stimulation
01/2022
1Adjuvant Chemotherapy
01/2021
1Neurosurgical Procedures
01/2017
1Drug Therapy (Chemotherapy)
12/2010